Journal of Pediatric and Adolescent Gynecology
Volume 20, Issue 3 , Pages 191-194, June 2007

Decidual Cast in a Girl Receiving Depot Medroxyprogesterone Acetate—A Case Report

Departments of Pathology, Pediatrics, and Gynecological Surgery, Children's Mercy Hospital, Kansas City, Missouri, USA

Abstract 

Background

The passage of tissue per vaginam in a young girl raises several diagnostic considerations that include aborted pregnancy, benign polyp, rhabdomyosarcoma, and rarely decidual cast.

Case

A 9-yr-old girl who was receiving depot medroxy-progesterone acetate to suppress menstruation passed tissue per vaginam. Pathological examination of the tissue showed a decidual cast with no chorionic villi, while a serum hCG test was also negative.

Conclusions

Decidual cast formation is a rare side effect of progestogen use and should be considered in the differential diagnosis of passage of tissue per vaginam.

Key Words: Decidual cast, Medroxyprogesterone, Side effect

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PII: S1083-3188(06)00276-2

doi:10.1016/j.jpag.2006.08.002

Journal of Pediatric and Adolescent Gynecology
Volume 20, Issue 3 , Pages 191-194, June 2007