Journal of Pediatric and Adolescent Gynecology
Volume 22, Issue 5 , Pages 292-299 , October 2009

Practice Variation in Screening for Sexually Transmitted Infections with Nucleic Acid Amplification Tests During Prepubertal Sexual Abuse Evaluations

  • Lisa S. Kresnicka, MD

      Affiliations

    • Division of Child Protection and Forensic Pediatrics, University of Florida, Jacksonville, Florida
    • Corresponding Author InformationAddress correspondence to: Lisa S. Kresnicka, MD
  • ,
  • David M. Rubin, MD, MSCE

      Affiliations

    • Safe Place: The Center for Child Protection and Health of the Division of General Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • Division of General Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • Clinical Virology Laboratory and Departments of Pediatrics and Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
  • ,
  • Kevin J. Downes, MD

      Affiliations

    • Division of General Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
  • ,
  • Jane M. Lavelle, MD

      Affiliations

    • Division of Pediatric Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • Clinical Virology Laboratory and Departments of Pediatrics and Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
  • ,
  • Richard L. Hodinka, PhD

      Affiliations

    • Clinical Virology Laboratory and Departments of Pediatrics and Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
  • ,
  • Karin L. McGowan, PhD

      Affiliations

    • Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
  • ,
  • Robert Grundmeier, MD

      Affiliations

    • Division of General Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
  • ,
  • Cindy W. Christian, MD

      Affiliations

    • Safe Place: The Center for Child Protection and Health of the Division of General Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • Division of General Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    • Clinical Virology Laboratory and Departments of Pediatrics and Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

References 

  1. Gaudiosi J. U.S. Department of Health and Human Services, Administration on Children, Youth and Families. Child Maltreatment 2005. Washington, DC: U.S. Government Printing Office; 2007;
  2. Ingram D, Everett V, Lyna P, et al. Epidemiology of adult sexually transmitted disease agents in children being evaluated for sexual abuse. Pediatr Infect Dis J. 1992;11:945
  3. Kellogg N. The evaluation of sexual abuse in children. Pediatrics. 2005;116:506
  4. American Academy of Pediatrics. Sexually transmitted diseases. In: 1997 Red Book: Report of the Committee on Infectious Diseases, (24th ed.). Edited by G Peter. Elk Grove Village, IL, Author, 1997, pp. 108–16.
  5. Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines 2002. MMWR Recomm Rep. 2002;51:1
  6. Siegel R, Schubert C, Myers P, et al. The prevalence of sexually transmitted diseases in children and adolescents evaluated for sexual abuse in Cincinnati: Rationale for limited STD testing in prepubertal girls. Pediatrics. 1995;96:1090
  7. Black C. Current methods of laboratory diagnosis of C. trachomatis infections. Clin Microbiol Rev. 1997;10:160
  8. Hammerschlag M. Appropriate use of nonculture tests for the detection of sexually transmitted diseases in children and adolescents. Semin Pediatr Infect Dis. 2003;14:54
  9. Girardet R, McClain N, Lahoti S, et al. Comparison of the urine-based ligase chain reaction test to culture for detection of C. trachomatis and Neisseria gonorrhoeae in pediatric sexual abuse victims. Pediatr Infect Dis J. 2001;20:144
  10. Workowski KA, Berman SM. Sexually transmitted diseases treatment guidelines. MMWR Recomm Rep. 2006;2006(55):1
  11. Adams J. Evolution of a classification scale: Medical evaluation of suspected child abuse. Child Maltreat. 2001;6:31
  12. Adams JA, Kaplan RA, Starling SP, et al. Guidelines for medical care of children who may have been sexually abused. J Pediatr Adolesc Gynecol. 2007;20:163
  13. Hammerschlag M. The transmissibility of sexually transmitted diseases in sexually abused children. Child Abuse Negl. 1998;22:623
  14. Ingram D, Everitt V, Flick L, et al. Vaginal gonococcal cultures in sexual abuse evaluations: Evaluation of selective criteria for preteenaged girls. Pediatrics. 1997;99:e8
  15. Shapiro RA, Schubert CJ, Myers PA. Vaginal discharge as an indicator of gonorrhea and chlamydia infection in girls under 12 years old. Pediatr Emerg Care. 1993;9:341
  16. Chernesky M, Jang D, Portillo E, et al. Abilities of APTIMA, AMPLICOR, and ProbeTec assays to detect Chlamydia trachomatis and Neisseria gonorrhoeae in PreservCyt ThinPrep Liquid-based Pap samples. J Clin Microbiol. 2007;45:2355
  17. Chernesky MA, Jang DE. APTIMA transcription-mediated amplification assays for Chlamydia trachomatis and Neisseria gonorrhoeae. Expert Rev Mol Diagn. 2006;6:519
  18. Chernesky MA, Martin DH, Hook EW, et al. Ability of new APTIMA CT and APTIMA GC assays to detect Chlamydia trachomatis and Neisseria gonorrhoeae in male urine and urethral swabs. J Clin Microbiol. 2005;43:127
  19. Gaydos CA, Quinn TC, Willis D, et al. Performance of the APTIMA Combo 2 assay for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in female urine and endocervical swab specimens. J Clin Microbiol. 2003;41:304

PII: S1083-3188(08)00229-5

doi: 10.1016/j.jpag.2008.07.003

Journal of Pediatric and Adolescent Gynecology
Volume 22, Issue 5 , Pages 292-299 , October 2009