Bilateral Ovarian Serous Borderline Tumor with a Giant Non-invasive Peritoneal Implant in a Four-Year-Old Girl

Njim, Leila; Moussa, Adnène; Saïdani, Zahra; Touil, Nada; Mlik, Latifa; Belghith, Mohsen; Zakhama, Abdelfattah

doi:10.1016/j.jpag.2009.08.008

« Previous Next »Journal of Pediatric and Adolescent Gynecology
Volume 23, Issue 1 , Pages e1-e4, February 2010

Bilateral Ovarian Serous Borderline Tumor with a Giant Non-invasive Peritoneal Implant in a Four-Year-Old Girl

Leila Njim, MD
- Department of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
- Address correspondence to: Dr. Leila Njim, Service d'Anatomie Pathologique, Hôpital Fattouma Bourguiba, Avenue du 1er juin, 5000 Monastir, Tunisie.
Adnène Moussa, MD
- Department of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
Zahra Saïdani, MD
- Department of Gynecology and Obstetrics, Fattouma Bourguiba University Hospital, Monastir, Tunisia
Nada Touil, MD
- Department of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
Latifa Mlik, MD
- Department of Pediatric Surgery, Fattouma Bourguiba University Hospital, Monastir, Tunisia
Mohsen Belghith, MD
- Department of Pediatric Surgery, Fattouma Bourguiba University Hospital, Monastir, Tunisia
Abdelfattah Zakhama, MD
- Department of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia

published online 19 October 2009.

Abstract

Epithelial ovarian tumors are uncommon before 20 years of age and rarely occur before puberty. The vast majority of these tumors are benign, and few cases of malignant and borderline tumors are described.

We report a case of a 4-year-old premenarchal girl, previously healthy, who presented with two abdominal masses. Laboratory analysis of blood showed elevation of the serum level of the CA-125. Ultrasonographic examination disclosed bilateral cystic ovarian masses. Laparoscopic exploration revealed bilateral ovarian multicystic masses with retro-uterine peritoneal implant. Bilateral salpingo-oophorectomy with implant resection was performed. Histologic findings were consistent with a serous borderline tumors of both ovaries and the peritoneal implant was of the non-invasive type. There is no evidence of recurrence at 3-year follow-up.

To our knowledge, there are only four cases of ovarian borderline tumors in premenarchal girls reported in the English literature: three of the mucinous type and only one of the serous type.

Key Words: Ovarian tumor, Premenarchal, Serous borderline tumor