Journal of Pediatric and Adolescent Gynecology
Volume 24, Issue 1 , Pages 35-38 , February 2011

Relationship between Weight and Bone Mineral Density in Adolescents on Hormonal Contraception

  • Andrea E. Bonny, MD

      Affiliations

    • Case Western Reserve University School of Medicine, Department of Pediatrics, MetroHealth Medical Center, Cleveland, Ohio, USA
    • Corresponding Author InformationAddress correspondence to: Andrea E. Bonny, MD, Department of Pediatrics, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109
    • ,
  • Michelle Secic, MS

      Affiliations

    • Secic Statistical Consultants, Chardon, Ohio, USA
    • ,
  • Barbara A. Cromer, MD

      Affiliations

    • Case Western Reserve University School of Medicine, Department of Pediatrics, MetroHealth Medical Center, Cleveland, Ohio, USA

References 

  1. O’Dell CM, Forke CM, Polaneczky MM, et al. Depot medroxyprogesterone acetate or oral contraception in postpartum adolescents. Obstet Gynecol. 1998;91:609
  2. Risser WL, Gefter LR, Barratt MS, et al. Weight change in adolescents who used hormonal contraception. J Adolesc Health. 1999;24:433
  3. Bonny AE, Britto MT, Huang B, et al. Weight gain, adiposity, and eating behaviors among adolescent females on depot medroxyprogesterone acetate (DMPA). J Pediatr Adolesc Gynecol. 2004;17:109
  4. Bonny AE, Secic M, Cromer BA. A longitudinal comparison of body composition changes in adolescent girls receiving hormonal contraception. J Adolesc Health. 2009;45:423
  5. Clark MK, Dillon JS, Sowers M, et al. Weight, fat mass, and central distribution of fat increase when women use depot-medroxyprogesterone acetate for contraception. Int J Obes (Lond). 2005;29:1252
  6. Berenson AB, Rahman M. Changes in weight, total fat, percent body fat, and central-to-peripheral fat ratio associated with injectable and oral contraceptive use. Am J Obstet Gynecol. 2009;200:329.e1
  7. Cromer BA, Blair JM, Mahan JD, et al. A prospective comparison of bone density in adolescent girls receiving depot medroxyprogesterone acetate (Depo-Provera), levonorgestrel (Norplant), or oral contraceptives. J Pediatr. 1996;129:671
  8. Busen NH, Britt RB, Rianon N. Bone mineral density in a cohort of adolescent women using depot medroxyprogesterone acetate for one to two years. J Adolesc Health. 2003;32:257
  9. Scholes D, LaCroix AZ, Ichikawa LE, et al. The association between depot medroxyprogesterone acetate contraception and bone mineral density in adolescent women. Contraception. 2004;69:99
  10. Tharnprisarn W, Taneepanichskul S. Bone mineral density in adolescent and young Thai girls receiving oral contraceptives compared with depot medroxyprogesterone acetate: a cross-sectional study in young Thai women. Contraception. 2002;66:101
  11. Lara-Torre E, Edwards CP, Perlman S, et al. Bone mineral density in adolescent females using depot medroxyprogesterone acetate. J Pediatr Adolesc Gynecol. 2004;17:17
  12. Cromer BA, Stager M, Bonny A, et al. Depot medroxyprogesterone acetate, oral contraceptives and bone mineral density in a cohort of adolescent girls. J Adolesc Health. 2004;35:434
  13. Cromer BA, Bonny AE, Stager M, et al. Bone mineral density in adolescent females using injectable or oral contraceptives: a 24-month prospective study. Fertil Steril. 2008;90:2060
  14. Reid IR. Relationships between fat and bone. Osteoporos Int. 2008;19:595
  15. Gomez-Ambrosi J, Rodriguez A, Catalan V, et al. The bone-adipose axis in obesity and weight loss. Obes Surg. 2008;18:1134
  16. Leonard MB, Shults J, Wilson BA, et al. Obesity during childhood and adolescence augments bone mass and bone dimensions. Am J Clin Nutr. 2004;80:514
  17. Hertzler AA, Trary RB. A dietary calcium rapid assessment method (RAM). Innovations in practice: a dietary calcium RAM. Top Clin Nutr. 1994;9:76
  18. Jeppsson S, Johansson EDB. Medroxyprogesterone acetate, estradiol, FSH and LH in peripheral blood after intramuscular administration of Depo-Provera to women. Contraception. 1976;14:461
  19. Klein KO, Larmore KA, de Lancy E, et al. Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children. J Clin Endocrinol Metab. 1998;83:3469

PII: S1083-3188(10)00208-1

doi: 10.1016/j.jpag.2010.06.007

Journal of Pediatric and Adolescent Gynecology
Volume 24, Issue 1 , Pages 35-38 , February 2011

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