Review Article| Volume 1, ISSUE 4, P221-229, 1988

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Applications of hormone receptors in obstetrics and gynecology

  • Deborah A. Metzger
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington, Connecticut
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  • Claude L. Hughes
    Address reprint requests to: Claude L. Hughes, Ph.D., M.D., Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC 27710, USA.
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina
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      Actions of all hormones are predominantly mediated by specific receptors. Progress in understanding the basic mechanisms of hormone-receptor interactions has led to several clinical applications of this receptor technology. Current applications include diagnosis and management of neoplasms of hormone-responsive tissues in the woman, diagnosis of previously inexplicable endocrine disorders, and development of new hormonal therapeutic agents. Our future diagnostic and therapeutic repertoire should continue to expand as these new molecular biology techniques mature.

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