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Abstract
Endocervical swabs from 137 asymptomatic girls 12–18 years of age (mean 16.1 years)
were tested for Chlamydia trachomatis using a direct fluorescent antibody (DFA) slide test (MicroTrak, Syva Co., Palo Alto,
CA) and compared with the tissue culture isolation of the organism. The DFA slides
were examined for quality of the specimen as well as for the presence of elementary
bodies. Of 137 slides, 5 (3.6%) were “poor” (less than 50 epithelial cells per well)
and were excluded from the analysis. The DFA test identified 26 (89.7%) of 29 culture-positive
specimens and 102 (99.0%) of 103 culture-negative specimens. The DFA test is a valuable
screening tool (positive predictive value 96.30%, negative predictive value 97.14%)
for identification of asymptomatic chlamydial cervical infection in adolescents when
slides are interpreted for adequacy of the specimen as well as the presence of elementary
bodies.
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References
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Article info
Footnotes
*Supported in part by Adolescent Health Training Grant (MCJ-000979-11-0) PHS and Program Project Grant (HD10699-11) NICHD.
**This paper was presented in part at the Second Annual meeting of the North American Society for Pediatric and Adolescent Gynecology held in Cleveland, OH, September 1987.
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Copyright
© 1988 Springer-Verlag New York Inc. Published by Elsevier Inc. All rights reserved.
