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Abstract
A case of McCune—Albright Syndrome in a 3½-year-old girl is presented. Although there
was clinical evidence of increased estrogen production, no steroid-dependent growth
phase was apparent on her growth velocity chart. Complications of polyostotic fibrous
dysplasia are discussed, and emphasis is placed on a multidisciplinary approach to
patients with McCune—Albright Syndrome.
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References
- Syndrome characterized by ostitis fibrosa disseminata, areas of pigmentation, and endocrine dysfunction with precocious puberty in females.N Engl J Med. 1937; 216: 727-746
- Absence of pubertal gonadotropin secretion in girls with McCune-Albright Syndrome.J Clin Endocrinol Metab. 1984; 58: 1161-1165
- Variable response to a long-acting agonist of luteinizing hormone-releasing hormone in girls with McCune-Albright Syndrome.J Clin Endocrinol Metab. 1984; 59: 801-805
- Treatment of precocious puberty in the McCune-Albright Syndrome with the aromatase inhibitor testolactone.N Engl J Med. 1986; 315: 1115-1119
- Cyclical ovarian function resistant to treatment with an analogue of luteinizing hormone releasing hormone in McCune—Albright Syndrome.N Engl J Med. 1984; 311: 1032-1036
- McCune—Albright Syndrome long term followup.JAMA. 1986; 256: 2980-2984
- The NIH experience with precocious puberty:diagnostic subgroups and response to short term luteinizing hormone releasing hormone analogue therapy.J Pediatr. 1986; 108: 47-54
- Fibrous dysplasia: a review of the disease and its manifestations in the temporal bone.Ann Otol Rhinol Laryngol (Suppl). 1982; 92: 1-52
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Copyright
© 1988 Springer-Verlag New York Inc. Published by Elsevier Inc. All rights reserved.