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Research Article| Volume 1, ISSUE 3, P185-189, 1988

Diagnostic efficacy of genitourinary symptoms and abnormal vaginal discharge for the recognition of lower genital tract infection in adolescent females

  • Daniel P. Krowchuk
    Correspondence
    Address reprint requests to: Daniel P. Krowchuk, M.D., Division of Adolescent Medicine, Department of Pediatrics, Cleveland Metropolitan General Hospital, 3395 Scranton Road, Cleveland, OH 44109, USA.
    Affiliations
    Division of Adolescent Medicine, Department of Pediatrics, Cleveland Metropolitan General Hospital, and Case Western Reserve University School of Medicine, Cleveland, Ohio
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  • Trina M. Anglin
    Affiliations
    Division of Adolescent Medicine, Department of Pediatrics, Cleveland Metropolitan General Hospital, and Case Western Reserve University School of Medicine, Cleveland, Ohio
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  • Robert M. Lembo
    Affiliations
    Division of Adolescent Medicine, Department of Pediatrics, Cleveland Metropolitan General Hospital, and Case Western Reserve University School of Medicine, Cleveland, Ohio
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      Abstract

      Clinicians frequently rely on a history of genitourinary symptoms or the appearance of vaginal discharge to diagnose infections of the vagina and cervix. To determine the diagnostic efficacy of these clinical criteria, we studied 254 unselected abolescent females presenting for reproductive health care. Of the 254 subjects, 105 (41%) had one or more lower genital tract infections (LGTI). Genitourinary symptoms were found to have a sensitivity of 48%, specificity of 78%, positive predictive value (PPV) of 61%, and negative predictive value (NPV) of 68% for the detection of LGTI. When abnormal vaginal discharge was used as an indicator of LGTI, the sensitivity was 65%, specificity 89%, PPV 81%, and NPV 78%. These data suggest that genitourinary symptoms and the appearance of vaginal discharge are inadequate indicators of the presence or absence of lower genital tract infection in adolescent females.

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      References

        • Bell TA
        Major sexually transmitted diseases of children and adolescents.
        Pediatr Infect Dis. 1983; 2: 153
        • Emans SJ
        Vulvovaginitis in children and adolescents.
        Pediatr Rev. 1981; 2: 319
        • Shafer MA
        • Beck A
        • Blain B
        • et al.
        Chlamydia trachomatis: Important relationships to race, contraception, lower genital tract infection, and Papanicolaou smear.
        J Pediatr. 1984; 104: 141
        • Shafer MA
        • Sweet RL
        • Ohm-Smith MJ
        • et al.
        Microbiology of the lower genital tract in postmenarchal adolescent girls: Differences by sexual activity, contraception, and presence of nonspecific vaginitis.
        J Pediatr. 1985; 107: 974
        • Fraser JJ
        • Rettig PJ
        • Kaplan DW
        Prevalence of cervical Chlamydia trachomatis and Neisseria gonorrhoeae in female adolescents.
        Pediatrics. 1983; 71: 333
        • Hunter CA
        • Long KR
        A study of the microbiological flora of the vagina.
        Am J Obstet Gynecol. 1958; 75: 865
        • Osborne NG
        • Grubin L
        • Pratson L
        Vaginitis in sexually active women: Relationship to nine sexually transmitted organisms.
        Am J Obstet Gynecol. 1982; 142: 962
      1. 8. Krowchuk DP, Anglin TM, Lembo R, et al: Use of enzyme immunoassay for the rapid diagnosis of Chlamydia trachomatis endocervical infection in adolescent females. J Adolesc Health Care (in press)

        • Amsel R
        • Totten PA
        • Spiegel CA
        • et al.
        Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations.
        Am J Med. 1983; 74: 14
        • Fletcher RH
        • Fletcher SW
        • Wagner EH
        Clinical Epidemiology: The Essentials. Williams and Wilkins, Baltimore1982: 41-58
        • Saltz GR
        • Linnemann CC
        • Brookman RR
        • et al.
        Chlamydia trachomatis cervical infections in female adolescents.
        J Pediatr. 1981; 98: 981
        • Bump RC
        • Sachs LA
        • Buesching WJ
        Sexually transmissible infectious agents in sexually active and virginal asymptomatic adolescent girls.
        Pediatrics. 1986; 77: 488
        • Chacko MR
        • Lovchik JC
        Chlamydia trachomatis infection in sexually active adolescents: Prevalence and risk factors.
        Pediatrics. 1984; 73: 836
        • Holmes KK
        Holmes KK Mardh P-A Wiesner PJ Lower genital tract infections in women: Cystitis/urethritis, vulvovaginitis, and cervicitis, Sexually Transmitted Diseases. McGraw-Hill, New York1984: 557-589