Case Report| Volume 22, ISSUE 4, e65-e68, August 2009

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Isolated Ovarian Relapse of Pre-B Acute Lymphoblastic Leukemia: A Case Report

Published:April 09, 2009DOI:



      Acute lymphoblastic leukemia is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace normal marrow hematopoietic cells, resulting in a marked decrease in the production of normal blood cells.

      Case Report

      We report a case of isolated ovarian relapse 7 years after the primary diagnosis in a patient, who was seemingly in clinical remission following unilateral ovariectomy and second-line chemotherapy.


      In contrast to testicular relapse, ovarian relapses in acute lymphoblastic leukemia are rarely reported. Surgical removal of the mass followed by chemotherapy is the therapeutic standard.

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