Abstract
Rare bleeding disorders can cause significant bleeding in children and adolescents.
These encompass rare clotting factor deficiencies, and fibrinolytic pathway defects.
Vascular anomalies can cause recurrent and refractory bleeding, and are included in
this review of rare causes of abnormal bleeding in children and adolescents. Menorrhagia
is often reported as a manifestation of these conditions. Succinct knowledge about
these disorders, their clinical presentation, diagnostic work-up, and therapeutic
options are crucial to the accurate diagnosis and optimal management of affected patients.
This review provides an overview of these infrequently encountered disorders, discusses
their recognition based on results of suggested screening tests and offers a general
guideline for approach to therapy.
Key Words
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Article info
Publication history
Published online: October 11, 2010
Footnotes
The authors have disclosed no conflicts of interest.
Identification
Copyright
© 2010 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.
