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Effect of Dietary Weight Loss on Menstrual Regularity in Obese Young Adult Women with Polycystic Ovary Syndrome

  • Tayseer M. Marzouk
    Affiliations
    Department of Maternity and Gynecology of Nursing, Faculty of Nursing, Mansoura University, Mansoura, Egypt
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  • Waleed A. Sayed Ahmed
    Correspondence
    Address correspondence to: Dr Waleed Ali Sayed Ahmed, MD, MRCOG, Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University, Round Road, Ismailia 41111, Egypt; Phone: +201091214406 (mobile), +2663334230 (landline); fax: +2 (064)3227426
    Affiliations
    Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
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Published:January 07, 2015DOI:https://doi.org/10.1016/j.jpag.2015.01.002

      Abstract

      Study Objective

      To investigate the effect of dietary weight loss on menstrual regularity in obese adolescent women with polycystic ovary syndrome (PCOS).

      Design and Setting

      A randomized controlled trial was held at the Faculty of Nursing, Mansoura University, and the Obesity Clinic of the Rheumatology Department at Mansoura University Hospitals between July 2011 and January 2013.

      Participants

      Sixty adolescent women with PCOS, body mass index (BMI) greater than 30, and complaints of menstrual irregularities were included in this study. Enrolled women were divided equally and randomly into 2 groups: intervention and control groups.

      Interventions

      Women in the intervention group (n = 30) were subject to an intensive dietary educational program with instructions to follow a conventional energy restricted diet, whereas women in the control group were instructed to follow the same healthy diet of the first group without calorie restriction.

      Main Outcome Measures

      Menstrual regularity, weight loss, the effect on waist circumference, and hirsutism score.

      Results

      The 2 groups were initially matched in average body weight, BMI, hirsutism score, and waist circumference. Six months later, there were significant decreases in all parameters in the weight reduction group. In addition, more menstrual episodes were recorded in the weight reduction compared with the control group (3.1 ± 1.2 vs. 2.3 ± 1.3; P = .010). Also, BMI, waist circumference, and hirsutism score were all significantly decreased at the end of the study.

      Conclusion

      Dietary weight loss in adolescent women with PCOS resulted in significant improvement in menstrual regularity, BMI, waist circumference, and hirsutism score.

      Key Words

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