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Case Report| Volume 30, ISSUE 3, P435-437, June 2017

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Lymphoblastic Lymphoma Presenting as Bilateral Ovarian Mass in an Adolescent Girl

Published:December 12, 2016DOI:https://doi.org/10.1016/j.jpag.2016.11.012

      Abstract

      Background

      Lymphomas rarely involve the genital tract and non-Hodgkin lymphoma (NHL) presenting as ovarian tumor is rare. Precursor B-cell lymphoblastic lymphoma arising from the ovary is extremely rare and to our knowledge, only 5 cases have been reported in the literature.

      Case

      A 15-year-old girl presented with bilateral ovarian masses, which, on biopsy proved to be precursor B-cell lymphoblastic lymphoma. She was treated with a Berlin-Frankfurt-Munster 90 protocol and she is alive in complete remission for more than 10 years.

      Summary and Conclusion

      NHL of the ovary should also be considered as a differential diagnosis in adolescent and young adults with ovarian masses. Attempt to make a preoperative diagnosis is crucial because ovarian NHL responds well to chemotherapy and has a good prognosis.

      Key Words

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      References

        • Yadav R.
        • Sharma M.C.
        • Karak A.K.
        • et al.
        Natural history of primary precursor B lymphoblastic lymphoma of the ovary: report of a rare case.
        J Obstet Gynaecol Res. 2013; 39: 611
        • Yildirim Y.
        Primary ovarian large B-cell lymphoma in patient with juvenile rheumatoid arthritis treated with low dose methotrexate.
        Gynecol Oncol. 2005; 97: 249
        • Fox H.
        • Langley F.A.
        • Govan A.D.
        • et al.
        Malignant lymphoma presenting as an ovarian tumour: a clinicopathological analysis of 34 cases.
        Br J Obstet Gynaecol. 1988; 95: 386
        • Maitra A.
        • McKenna R.W.
        • Weinberg A.G.
        • et al.
        Precursor B-cell lymphoblastic lymphoma. A study of nine cases lacking blood and bone marrow involvement and review of the literature.
        Am J Clin Pathol. 2001; 115: 868
        • Iyengar P.
        • Ismiil N.
        • Deodhare S.
        Precursor B-cell lymphoblastic lymphoma of the ovaries: an immunohistochemical study and review of the literature.
        Int J Gynecol Pathol. 2004; 23: 193
        • Sakurai N.
        • Tateoka K.
        • Taguchi J.
        • et al.
        Primary precursor B-cell lymphoblastic lymphoma of the ovary: case report and review of the literature.
        Int J Gynecol Pathol. 2008; 27: 412
        • Zhao X.Y.
        • Hong X.N.
        • Cao J.N.
        • et al.
        Clinical features and treatment outcome of 14 cases of primary ovarian non Hodgkin’s lymphoma: a single centre experience.
        Med Oncol. 2011; 28: 1559
        • Yamada T.
        • Iwao N.
        • Kasamatsu H.
        • et al.
        A case of malignant lymphoma of the ovary manifesting like an advanced ovarian cancer.
        Gynecol Oncol. 2003; 90: 215