Abstract
Background
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Relapse
of ALL occurs in 15%-20% of patients, with 2%-6% occurring exclusively in extramedullary
sites. Relapse of ALL in gynecologic organs is extremely rare.
Case
We present a case of a 12-year-old girl with a history of ALL who was referred to
the pediatric gynecology clinic with abnormal uterine bleeding. She was determined
to have an extramedullary uterine relapse of her ALL.
Summary and Conclusion
Abnormal uterine bleeding in the setting of childhood malignancy is a frequent reason
for consultation to pediatric and adolescent gynecology services. This bleeding is
commonly attributed to thrombocytopenia due to bone marrow suppressive chemotherapeutic
agents. However, as shown in this report, abnormal uterine bleeding might be a manifestation
of an extramedullary relapse.
Key Words
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Article info
Publication history
Published online: January 03, 2017
Footnotes
None of the authors have a conflict of interest.
Identification
Copyright
© 2017 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc.
