Abstract
Study Objective
To explore the prevalence, mortality, and spatial distribution of gastroschisis using
a large population-based sample with cases identified according to birth and death
certificates (ICD-10 diagnosis code Q79.3, gastroschisis) through the General Directorate
of Health Information of the Secretary Health of Mexico, over the course of a 15-year
period.
Design, Setting, Participants, Interventions, and Main Outcome Measures
A descriptive study examining 10,287 cases of gastroschisis was performed from 2000-2014
using public natality data for denominators (more than 25 million live births). Gastroschisis
prevalence and mortality was calculated for each of year, state, maternal, and newborn
characteristics. Spatial distribution was analyzed according to gastroschisis prevalence
in the 32 states of Mexico.
Results
Gastroschisis prevalence was 4.01 per 10,000 live births (annual trend 2.09-6.85).
Mortality associated with gastroschisis was 1.28 per 10,000 live births. Women younger
than 20 years old, primiparae, and preterm infants had the highest gastroschisis-related
prevalence (13.12, 5.83, and 7.51 per 10,000 live births, respectively). Gastroschisis
prevalence and mortality did not differ according to newborn sex. A negative binomial
distribution, variance (82,391.87) greater than the mean (321.47) was identified.
Conclusion
Our findings show an increasing temporal trend for gastroschisis since 2000 in Mexico.
Additionally, gastroschisis might follow in future instances a positive binomial or
Poisson distribution. Therefore, improving surveillance of risk factors and supporting
research for gastroschisis is warranted among maternal age younger than 25, particularly,
younger than 20 years of age.
Key Words
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Article info
Publication history
Published online: January 06, 2018
Footnotes
The authors indicate no conflicts of interest. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Secretary of Health of Mexico.
Identification
Copyright
© 2018 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc.
