Abstract
Background
Bone marrow transplantation is a lifesaving procedure for a range of serious benign
or malignant hematological conditions. A proportion of patients, however, will develop
graft vs host disease (GVHD), acute or chronic, with serious long-term sequalae.
Cases
We present 2 cases of hematocolpos that developed in adolescence because of vaginal
synechiae due to GVHD. The condition was initially asymptomatic, resolved spontaneously
at first and recurred. In 1 girl blunt lysis of the adhesions was performed with the
patient under general anesthesia, followed thereafter by local hydrocortisone and
estriol treatment.
Summary and Conclusion
Genital symptoms might not be readily reported by adolescents after bone marrow transplantation.
Physicians should be aware of possible late effects of GVHD on genitalia, inquire
about symptoms, and be acquainted with addressing complications, such as vaginal obstruction.
Key Words
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References
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Article info
Publication history
Published online: May 29, 2018
Footnotes
The authors indicate no conflicts of interest.
This work was presented, in part, as a poster at the 44th Annual Meeting of the European Bone Marrow Transplantation, March 18-21, 2018, Lisbon, Portugal (reference number A-947-0015-01289).
Identification
Copyright
© 2018 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc.
