Aromatase inhibitors (AIs) have been utilized for a number of estrogen-modulated conditions, including hormone-sensitive breast cancer, endometriosis and ovulation induction. Some borderline ovarian tumors (BOT) are estrogen-receptor positive, and case reports suggest the use of AIs in the prevention of recurrent serous BOT. We present a case of progression from mucinous cystadenoma to mucinous BOT after two prior cystectomies in whom an AI was used and the patient is now 2 years without recurrent disease.
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