Vulvovaginal (vv) graft-versus-host disease (GVHD) is a serious complication of allogenic
hematopoietic stem cell transplant (HSCT) that results in vulvar irritation, vaginal
stenosis (VS), and menstrual outflow obstruction (MOO). The incidence of vvGVHD post-HSCT
is as high as 49%, 2 years post-HSCT in adult women; however, data on the pediatric
population is lacking. We aimed to identify the prevalence of vvGVHD, the surveillance
of potential genital complications, and the referral of pediatric patients post-HSCT
to pediatric and adolescent gynecology (PAG).
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