Case Report| Volume 32, ISSUE 3, P337-338, June 2019

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An Adolescent Girl with a Complaint of Clitoral Swelling

Published:February 08, 2019DOI:



      We present the case of an adolescent girl with prominent clitoral swelling as the first symptom when she presented to the emergency department, and who was subsequently diagnosed with nephrotic syndrome.


      A 14-year-old adolescent girl was admitted with painless clitoral swelling. She denied recent masturbation, itching, or discharge. She was within the last few days of menstruation. Physical examination revealed clitoral edema without erythema or genital edema. Urine dipstick test and microscopic evaluation revealed protein 2+, blood 3+, abundant erythrocytes and 9–10 leukocytes. A few days later, additional clinical findings, such as pretibial and facial edema, were diagnosed as nephrotic syndrome.

      Summary and Conclusion

      This case is a reminder that clitoral swelling is to be considered a sign in the diagnosis of nephrotic syndrome, even when it occurs alone.

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        • Carter J.L.
        • Tomson C.R.
        • Stevens P.E.
        • et al.
        Does urinary tract infection cause proteinuria or microalbuminuria? A systematic review.
        Nephrol Dial Transplant. 2006; 21: 3031
        • Bacon J.L.
        • Burgis J.T.
        Hair thread tourniquet syndrome in adolescents: a presentation and review of the literature.
        J Pediatr Adolesc Gynecol. 2005; 18: 155
        • Heller D.S.
        Lesions of clitoris: a review.
        J Low Genit Tract Dis. 2015; 19: 68
        • Ch’ng T.W.
        • Umpaichitra V.
        A case of unusual clitoromegaly.
        J Pediatr Adolesc Gynecol. 2018; 31: 543
        • Downie M.L.
        • Gallibois C.
        • Parekh R.S.
        • et al.
        Nephrotic syndrome in infants and children: pathophysiology and management.
        Paediatr Int Child Health. 2017; 15: 1
        • Teoh C.W.
        • Robinson L.A.
        • Noone D.
        Perspectives on edema in childhood nephrotic syndrome.
        Am J Physiol Renal Physiol. 2015; 309: 575