ABSTRACT
Background
Two concurrent malignancies present in a young person is an extremely rare condition.
Diagnoses of gastric cancer primarily concern older patients. There are very few reports
of concomitant Krukenberg tumor and germ-cell ovarian malignancy.
Case
A 19-year-old girl was admitted to the gynecologic oncology department with symptoms
of advanced malignancy. Radiological imaging revealed disseminated neoplastic disease
with bulky adnexal tumors. Cytoreductive surgery was performed, achieving no visible
disease (T = 0 cm). The final pathology report confirmed metastatic mixed adenoneuroendocrine
carcinoma (MANEC) in both ovaries, originating from the gastrointestinal tract. Moreover,
the primary germ cell yolk sac tumor was found in the left ovary.
Conclusion
In cases of concomitant gastric and ovarian tumors, metastatic disease (Krukenberg
tumor) should be considered in the differential diagnosis. This concerns even adolescent
patients. In particular cases, including tumors with germ cell components, primary
debulking surgery is crucial for prognosis.
Key Words
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Article info
Publication history
Published online: March 05, 2021
Accepted:
February 22,
2021
Received in revised form:
January 31,
2021
Received:
November 28,
2020
Footnotes
The authors declare that they have no competing interests.
Identification
Copyright
© 2021 Published by Elsevier Inc. on behalf of North American Society for Pediatric and Adolescent Gynecology.
