Dr. Ashour and colleagues
1.recently published a randomised clinical trial on the management of intrauterine device (IUD) insertion. In a 3-arm clinical trial, they randomized nulliparous women prior to Copper T380A IUD insertion to pretreatment with vaginal misoprostol, vaginal dinoprostone, or placebo. The active treatments were 1 tablet of misoprostol 200 mg vaginally (Misotac; Sigma Pharma, SAE, Egypt), and one tablet of dinoprostone 3 mg vaginally (Prostin E2, Pharmacia & Upjohn, Puurs, Belgium), respectively. With respect to placebo, the authors write “participants in the placebo group received 1 tablet of placebo vaginally, which was identical to study drugs.”
- Ashour ASA
- El Sharkawy M
- Ali AS
- et al.
Comparative efficacy of vaginal misoprostol vs vaginal dinoprostone administered 3 hours prior to Copper T380A intrauterine device insertion in nulliparous women: a randomized controlled trial.
J Pediatr Adolesc Gynecol. 2020; 33: 559
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- Comparative efficacy of vaginal misoprostol vs vaginal dinoprostone administered 3 hours prior to Copper T380A intrauterine device insertion in nulliparous women: a randomized controlled trial.J Pediatr Adolesc Gynecol. 2020; 33: 559
Published online: March 22, 2021
Accepted: February 2, 2021
Received: February 1, 2021
© 2021 Published by Elsevier Inc. on behalf of North American Society for Pediatric and Adolescent Gynecology.