Dear Editor,
We would like to share ideas on “Vulvar Aphthous Ulcer Following Pfizer-BioNTech COVID-19 Vaccine - A Case Report.
1.
Drucker et al concluded the following: “Summary and conclusion- Vaccination, in general, has been associated with….caused by a similar mechanism and should be considered a rare side effect of this vaccine.”- Drucker A
- Corrao K
- Gandy M:
Vulvar aphthous ulcer following Pfizer-BioNTech COVID-19 vaccine - a case report.
J Pediatr Adolesc Gynecol. 2021 Oct 27; (S1083-3188(21)00325-9Online ahead of print)https://doi.org/10.1016/j.jpag.2021.10.007
1.
A mucocutaneous effect of COVID-19 vaccination is possible. The pathogenesis is still inconclusive. For post-CPVOD-19 vaccination vulvar aphthous ulcer, further investigation and monitoring of clinical symptoms is necessary. The genital ulcer might be the first presentation of Behcet's disease, which is a rare problem observed following COVID-19 vaccination.- Drucker A
- Corrao K
- Gandy M:
Vulvar aphthous ulcer following Pfizer-BioNTech COVID-19 vaccine - a case report.
J Pediatr Adolesc Gynecol. 2021 Oct 27; (S1083-3188(21)00325-9Online ahead of print)https://doi.org/10.1016/j.jpag.2021.10.007
2.
For a possible pathogenesis, COVID-19 vaccination can induce a hyperviscosity problem,- Tagini F
- Carrel L
- Fallet B
- et al.
Behcet's-like adverse event or inaugural Behcet's disease after SARS-CoV-2 mRNA-1273 vaccination?.
Rheumatology (Oxford). 2021 Oct 7; (Online ahead of print): keab751https://doi.org/10.1093/rheumatology/keab751
3.
which is a rare but possible clinical problem associated with Behcet's disease.4.
Declaration of Competing Interest
None
References
- Vulvar aphthous ulcer following Pfizer-BioNTech COVID-19 vaccine - a case report.J Pediatr Adolesc Gynecol. 2021 Oct 27; (S1083-3188(21)00325-9Online ahead of print)https://doi.org/10.1016/j.jpag.2021.10.007
- Behcet's-like adverse event or inaugural Behcet's disease after SARS-CoV-2 mRNA-1273 vaccination?.Rheumatology (Oxford). 2021 Oct 7; (Online ahead of print): keab751https://doi.org/10.1093/rheumatology/keab751
- Expected viscosity after COVID-19 vaccination, hyperviscosity and previous COVID-19.Clin Appl Thromb Hemost. Jan-Dec 2021; 27 (10760296211020833)
- Haemorheological alterations in Behcet's disease are not related to a tendency for venous thrombosis.Thromb Res. 2005; 115: 399-404
Article info
Publication history
Published online: December 31, 2021
Accepted:
November 29,
2021
Received:
November 1,
2021
Identification
Copyright
© 2021 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.
