ABSTRACT
Background
The surgical treatment of girls with cervical atresia and complete absence of the
vagina remains a problem because of the rarity of cases and the controversial study
results.
Objective
To describe the surgical technique and long-term results of laparoscopically assisted
uterovestibular anastomosis in patients with cervical atresia and complete absence
of the vagina
Study Design
Sixteen consecutive patients with cervical atresia and complete absence of the vagina
were conservatively treated with laparoscopically assisted uterovestibular anastomosis
in 2 tertiary care referral centers. The follow-up assessments included clinical examination,
determination of the presence and quality of sexual intercourse, and vaginoscopy.
Results
All patients underwent laparoscopically assisted uterovestibular anastomosis. No perioperative
complications occurred. The mean follow-up period was 8 ± 3.2 years. In all patients,
the length of the neovagina was greater than 4 cm at 1 year after the surgery and
approximately 6 cm after 2 years. After the start of sexual intercourse, the neovagina
exceeded 7 cm in length in 2 of the 11 sexually active patients. At 12 months after
the surgery, iodine-positive epithelium was present in all patients and was maintained
over time. The continuity of the neovagina, neocervix, and uterine body was maintained
without further interventions in 15 of the 16 patients. During the follow-up, 11 patients
were sexually active, 5 were married, 4 were seeking conception, and 2 had spontaneous
pregnancy.
Conclusions
Laparoscopically assisted uterovestibular anastomosis seems to be a safe and effective
treatment for patients with cervical atresia and complete absence of the vagina, at
least in terms of the recovery of menstrual function and sexual activity.
Key Words
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Pediatric and Adolescent GynecologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Congenital cervical atresia: report of seven cases and review of the literature.Am J Obstet Gynecol. 1997; 177: 1419-1425
- Successful end to end cervicovaginal anastomosis in a patient with congenital cervical fragmentation: case report.Hum Reprod. 2004; 19: 1204-1210
- Mullerian anomalies and their management.Fertil Steril. 1983; 40: 159-163
- Reconstructive surgery for congenital atresia of the uterine cervix.Fertil Steril. 1976; 27: 1277-1282
- Barrette G, Lewlewiwichz R: Congenital atresia of the uterine cervix and vagina: three cases.Fertil Steril. 1980; 33: 25-29
- Congenital atresia of the uterine cervix.Obstet Gynecol. 1973; 42: 213-217
- Gordts G, Grigoris F, Grimbizis GF: Current knowledge about the management of congenital cervical malformations: a literature review.Fertil Steril. 2020; 113: 723-732
- Congenital anomalies of the uterine cervix: lessons from 30 cases managed clinically by a common protocol.Fertil Steril. 2010; 94: 1858-1863
- Success following vaginal creation for Mullerian agenesis.Fertil Steril. 1983; 39: 809-813
- Neovaginal mucosa after Vecchietti's laparoscopic operation for Rokitansky syndrome: structural and ultrastructural study.Am J Obstet Gynecol. 2006; 195: 56-61
- Laparoscopically assisted uterovestibular anastomosis in patients with uterine cervix atresia and vaginal aplasia.Fertil Steril. 2008; 89: 212-216
- Die Neovagina beim Rokitanksy-Küster-Hauser-Syndrom [Neovagina in Rokitanksy-Küster-Hauser syndrome].Gynakologe. 1980; 13: 112-115
- Neovaginal mucosa after Vecchietti's laparoscopic operation for Rokitansky syndrome: structural and ultrastructural study.Am J Obstet Gynecol. 2006; 195: 56-61
- Surgical correction of congenital atresia of the cervix.Am J Obstet Gynecol. 1958; 76: 643-646
- Atresia cervicis uteri congenita [Congenital atresia of the uterine cervix].Nord Med. 1966; 75: 41-42
- Pregnancy following the surgical correction of congenital atresia of the cervix.Intb J Gynaecol Obstet. 1973; 11: 143
- Utero-vaginal anastomosis in women with uterine cervix atresia: long-term follow-up and reproductive performance. A study of 18 cases.Hum Reprod. 2001; 16: 1722-1725
- Pregnancies after reconstructive surgery for congenital cervicovaginal atresia.Am J Obstet Gynecol. 2000; 183: 421-423
- Colon replacement of vagina to restore menstrual function in 11 adolescent girls with vaginal or cervicovaginal agenesis.Pediatr Surg Int. 2009; 25: 675-681
- Cervicovaginal anastomosis by Gore-Tex in Mullerian agenesis.Arch Gynecol Obstet. 2015; 291: 467-472
- McIndoe A: The treatment of congenital absence and obliterative conditions of the vagina.Br J Plast Surg. 1950; 2: 254
- Bedner R, Rzepka-Gorska I, Blogowska A, et al: Effects of a surgical treatment of congenital cervicovaginal agenesia.J Pediatr Adolesc Gynecol. 2004; 17: 327-330
- Combined retropubic balloon vaginoplasty and laparoscopic canalization: a novel blend of techniques provides a minimally invasive treatment for cervicovaginal aplasia.Am J Obstet Gynecol. 2009; 201 (e1-5): 333
- Outcomes in patients undergoing robotic reconstructive uterovaginal anastomosis of congenital cervical and vaginal atresia.Int J Med Robot. 2017; 13: 1821
- Vaginoplasty with oxidized cellulose: anatomical, functional and histological evaluation.Eur J Obstet Gynecol Reprod Biol. 2012; 163: 204-209
Article info
Publication history
Published online: April 27, 2022
Accepted:
April 20,
2022
Received in revised form:
April 14,
2022
Received:
July 14,
2021
Identification
Copyright
© 2022 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.